The Tennessee Institute of Regenerative Medicine (TennIRM) and the Division of Regenerative and Rehabilitation Sciences in the College of Health Professions welcomes Dr. Sriram Ravindran, Associate Professor in the Department of Oral Biology in the College of Dentistry at the University of Illinois Chicago. His research has focused on the role of the extracellular matrix (ECM) in stem cell behavior and matrix mineralization. Specifically, he has examined how the ECM's tissue-specific uniqueness can influence the fate of stem cells. He designs 3D scaffolds and modifies existing clinical materials by incorporating native cell-type-specific ECM and cell-type-specific exosomes on/within them to control stem cell differentiation and tissue regeneration. He holds a patent for technology to develop biomimetically enhanced demineralized bone matrices and titanium implants and is investigating the mass production and clinical translation use of these biomimetic techniques.

His seminar is titled “Engineering and Delivery of Mesenchymal Stem Cell Derived Extracellular Vesicles for Bone Repair”